After a treatment (microneedling, laser, a chemical peel) your skin is in a state of controlled repair. The faster and more completely it recovers, the stronger the result. The Regenerative Face Serum is built for exactly that window. Powered by PXR-9™ (our proprietary growth factor complex of five human-identical proteins delivered via plant-derived exosomes), it restores the cellular communication that estrogen used to drive: faster barrier recovery, stronger collagen production, and a skin surface that starts behaving younger. For post-menopausal skin, this isn't anti-aging. It's cellular restoration.

Most anti-aging serums are formulated for skin that's aging gradually. Renève is formulated for skin that changed quickly - the accelerated thinning, laxity, and dryness that follow the hormonal shift of menopause.
PXR-9™ is the only growth factor complex developed specifically to address estrogen-deprived skin cells - and The Regenerative Face Serum delivers it at the concentration that makes a measurable difference.
Shop NowMost serums sit on top of your skin and hydrate the surface. The Regenerative Face Serum works differently. Powered by PXR-9™ (our proprietary growth factor complex), it delivers signals directly to your skin cells, telling them to repair, rebuild, and regenerate. Faster recovery after treatments. Stronger collagen over time. Skin that starts behaving younger.
Whether you've had microneedling, laser, or a chemical peel, your skin is in a state of controlled inflammation. PXR-9™ accelerates that recovery window, calming redness, rebuilding the barrier, and shortening the time between your treatment and visible results.
PXR-9™ growth factors signal your skin cells to produce more of their own collagen and elastin, the structural proteins that give skin its firmness and bounce. Used consistently, the serum doesn't just treat the surface. It rebuilds what's been lost underneath.
PXR-9™ growth factors perform best in a hydrated skin environment. The formula maintains moisture at every depth: immediate surface plumping you can see, and deeper moisture retention that lasts. Post-menopausal skin loses the ability to retain moisture faster than younger skin. This isn't just a hydration benefit. It's the environment PXR-9™ needs to work.
A compromised barrier is what stops active ingredients before they reach their target. The formula includes barrier-repair actives specifically to keep the absorption pathway open for PXR-9™. In post-menopausal skin, where the barrier is chronically thinner, maintaining its integrity isn't a bonus. It's the difference between growth factors reaching skin cells and not. No fragrance, no sensitisers.

After menopause, estrogen levels drop - and your skin cells lose one of their primary signals to repair and renew. PXR-9™ was developed specifically to fill that gap.
By delivering human-identical growth factors through a plant-based exosome delivery system, it restores the cellular communication your skin has been missing - so your cells start behaving the way they did when estrogen was doing the work.
See The FormulaPXR-9™ combines growth factor science, exosome delivery, and multi-weight hydration into a formula built around the specific needs of post-menopausal skin.
Five synthesised, human-identical growth factors - the same signalling proteins your skin produced naturally before hormonal change. They tell your skin cells to repair damage, produce collagen, and regenerate tissue. Delivered through plant-derived exosomes, they reach the cells that need them, not just the surface.
Growth factors are large molecules. Without a delivery mechanism, they don't penetrate deeply enough to work. PXR-9™ encapsulates its growth factors inside plant-derived exosomes: microscopic carriers that travel between cells and release their payload where it's needed. This is the same principle used in advanced treatments, now in a daily serum.
High molecular weight plumps and smooths immediately - you see it from the first use. Low molecular weight goes deeper, binding water inside the skin where PXR-9™ does its work. Post-menopausal skin loses moisture faster than younger skin. This addresses both what you can see and what you can't.
The Regenerative Face Serum is fragrance-free, dye-free, and formulated without known irritants - safe for skin recovering from procedures, and for the reactive, barrier-compromised skin that often accompanies hormonal change.

Five synthesised, human-identical growth factors (EGF, IGF-1, Acidic FGF, Basic FGF, VEGF) delivered via plant-derived exosomes. Signals skin cells to repair, regenerate, and rebuild collagen. The foundation of every Renève formula.

A combination of high and low molecular weight hyaluronic acid. High molecular weight plumps and smooths the surface immediately. Low molecular weight penetrates deeper to bind moisture inside the skin for lasting hydration and firmness. Post-menopausal skin loses hyaluronic acid faster than younger skin. This dual-weight complex addresses both the immediate dryness you can see and the deeper moisture deficit that affects how well PXR-9™ performs.

Calms redness, reduces inflammation, and actively repairs the skin's outer barrier. Particularly valuable post-procedure, when the barrier is temporarily compromised and the skin is at its most reactive. In post-menopausal skin, where the barrier is chronically thinner, Panthenol maintains the skin integrity that allows PXR-9™ growth factors to be absorbed and used at their full effectiveness.

Designed for daily use, morning and evening, as the active step in your routine. For post-procedure use, apply as directed by your practitioner, typically once the skin's barrier has begun to close.
Apply to clean, dry skin. Remove all traces of SPF, makeup, or previous products before application. A clean surface allows the growth factors to absorb without interference.
Dispense 3–4 drops into your palm. Press gently into the face and neck using your fingertips. No rubbing. The lightweight liquid absorbs almost immediately. Allow 60 seconds before the next step.
Follow with your moisturiser or treatment cream to seal in the growth factors and support the barrier. In the morning, finish with SPF. PXR-9™ continues working beneath every layer. Its cellular signalling doesn't require direct contact with air or light.
Cellular regeneration takes time. The results you see in the first week are the surface response. The deeper structural changes - new collagen, a rebuilt barrier, firmer tissue - build over months of consistent use.

Redness calms, skin feels more comfortable and hydrated. The barrier begins to strengthen. If used post-procedure, recovery feels visibly faster - less downtime, more even healing.

Skin texture becomes more refined. Fine lines appear softer. Skin looks more even and plumper - a result of both the hyaluronic acid complex and the early collagen response triggered by PXR-9™.

Measurable improvement in skin firmness and density. The structural rebuild that PXR-9™ initiates at the cellular level becomes visible at the surface. Skin looks and feels like a more resilient, more youthful version of itself.
Most anti-aging serums are formulated for skin that's aging gradually. Renève is formulated for skin that changed quickly: the accelerated thinning, laxity, and dryness that follow the hormonal shift of menopause. PXR-9™ is the only growth factor complex developed specifically to address estrogen-deprived skin cells, and The Regenerative Face Serum delivers it at the concentration that makes a measurable difference.
Five Human-Identical Growth FactorsNot plant extracts, not peptide mimics, but the actual signalling proteins your skin recognises.
Delivered Via Plant-Derived ExosomesSo they reach the cells that need them, not just the surface.
Developed For Post-Menopausal Skin SpecificallyNot adapted from a general anti-aging formula.
100% Vegan And Cruelty-FreeNo mammalian-derived stem cells or placental extracts.

We measured the Regenerative Face Serum against leading serums on the features that actually determine whether a formula works for post-menopausal skin.

The Regenerative Face Serum is the foundation of the Renève system. Use it alone or as the active serum step within a full Renève regimen.
1 Unit
$115
2 Units
$210
Save 9%
3 Units
$295
Save 14%
We want you to see what PXR-9™ does for your skin: faster recovery, stronger collagen, a barrier that holds. If after 60 days of consistent daily use you don't see a measurable difference, send it back for a full refund. No forms. No awkward questions. No expiry on the promise.
Start Your RebuildPXR-9™ is Renève's proprietary growth factor complex - five human-identical growth factors delivered via plant-derived exosomes. After menopause, estrogen-driven cellular repair slows significantly. PXR-9™ restores the signalling that tells your skin cells to repair and regenerate, picking up where your hormones left off.
Daily use: apply after cleansing, before your moisturiser, morning and evening. Post-procedure: apply once your practitioner confirms the skin barrier has begun to close - typically 24–48 hours after microneedling, laser, or chemical peel. The growth factors accelerate the recovery phase without irritating compromised skin.
Yes. The formula is fragrance-free, dye-free, and formulated without known sensitisers. Panthenol actively reduces inflammation and supports barrier repair, making it particularly well-suited for reactive, post-menopausal, or post-procedure skin.
Most growth factor serums are formulated for general aging. The Regenerative Face Serum was developed specifically for estrogen-deprived skin - the accelerated thinning, laxity, and barrier compromise that follow menopause. PXR-9™ is the only growth factor complex built around that specific cellular profile.
Yes. Apply it as your active serum step - after cleansing and before moisturiser. It layers well under any treatment cream or SPF. Avoid layering directly with strong acids (AHAs/BHAs) in the same step; use those on alternate evenings if needed.
A full refund if you're not satisfied with your results after 60 days of consistent daily use. We ask for a minimum of 14 days before initiating a return. Returns accepted within 70 days of delivery. No forms, no conditions, full refund.